Wholesale of pet supplies

IN-UP complex for dogs weighing 10-20 kg

IN-UP complex is a therapeutic and prophylactic antiparasitic agent that possesses a complex insectoacaricidal and anthelmintic activity against larval and sexually mature development phases of ectoparasites (fleas, ixodid ticks, lice, chewing lice) and endoparasites (round- and tapeworms) parasitizing in dogs. IN-UP complex is available in the form of a solution for external use.

The drug provides the longest protection of animal from parasites among competitive brands – up to 50 days.

Drugs trademark of the IN-UP complex are profitable to sell

High profit

IN-UP complex trademark products are in demand among retail companies and end customers, and will provide your organization with a high profit from their sales.

Promotion cost savings

The manufacturer of IN-UP complex conducts a comprehensive promotion of this brand: online promotion events are organized, lectures and presentations are regularly held in the Russian cities to help us learn more about the benefits of working with IN-UP complex drugs and to increase their sales.

High demand

The uniqueness of IN-UP complex drugs: the absence of competitors in the spectrum of action and duration of protection against parasites among domestic products ensure a high demand for this drug among the end customers.


The drug is intended for treatment and prevention of infections caused by fleas, ixodid ticks, lice, chewing lice, round (including microfilariae) and tapeworms.


1 ml of the drug contains:

  • Aversectin С1 – 4 mg;
  • Fipronil – 50 mg;
  • Praziquantel – 100 mg.

Dosage form

Neck drops.


2-ml polymer dropper vials with a tamper evident cap. Dropper vials are packed in cardboard boxes and provided with instructions for use. 1 show box contains 5 vials.

Storage conditions, shelf life

Store with caution in a closed manufacturer’s packaging, separate from food and feed, in a dry place, protected from direct sunlight, in places out of children’s and animal’s reach at a temperature from 0 to +25 °C.

The shelf life: 2 years.


IN-UP complex should not be used in puppies younger than 2 months of age, pregnant and nursing female dogs, animals with infectious diseases and recovering animals, as well as simultaneously with other antiparasitic drugs.

It is not recommended to use the drug in Collies, Shelties, and Bobtail breeds due to their increased sensitivity to avermectins.

The drug should be used with caution to animals with hypersensitivity to its components. Before the first use of the drug, it is recommended to conduct a sensitivity test. This will prevent the development of symptoms of individual hypersensitivity. For the test, the drug is prescribed at a reduced dose. If the animal’s condition is normal, after a while the dose is adjusted to therapeutic.

Pharmacological properties

IN-UP complex possesses insecticidal and anthelmintic activity against larval and sexually mature development phases of fleas, ixodid ticks, lice, chewing lice, round- and tapeworms that parasitize in animals.

The therapeutic effect of IN-UP complex is caused by pharmacological properties of the active substances in its composition.

Aversectin C1 has a pronounced insectoacaricidal effect against fleas, ixodid ticks, lice, chewing lice, and anthelmintic action against roundworms (including microfilariae). Aversectin C1 is absorbed from the site of application, enters the circulatory system of the animal's body, and produces antiparasitic effect in the tissues and organs. The mechanism of action of aversectin C1 consists in blocking the transmission of nerve impulses, causing paralysis of the muscles and further death of parasites.

Fipronil has a pronounced insectoacaricidal effect against fleas, ixodid ticks, lice, and chewing lice. Fipronil does not enter into the systemic bloodstream of the body; it is deposited in the epidermis, hair follicles, sebaceous glands of the animal's skin, and then is released to the surface of the body along with the secret of the glands, destroying ectoparasites on the pets. The mechanism of fipronil action consists in impairment of the transmission of nerve impulses, resulting in paralysis of the muscular system and the death of fleas, ticks, lice, and chewing lice.

Praziquantel has an anthelmintic effect against tapeworms. Praziquantel is absorbed from the site of application, then it enters the circulatory system of the animal's body, is secreted into the intestines, and destroys endoparasites. The mechanism of praziquantel action is based on the destruction of tapeworm tissues, spastic paralysis and subsequent death of parasites.

Usage and dosage

IN-UP complex is used once by applying on a dry undamaged skin. After moving aside the hair, apply the drug on the skin at several points in the back between the shoulder blades (in places inaccessible for licking).

For complex destruction of fleas, ixodid ticks, chewing lice, round- (including microfilariae) and tapeworms, animals weighing 10-20 kg are treated once at the dose of 2.0 ml.

In order to destroy ixodid ticks on the animal's body, apply 1 drop of the drug on the tick and on the place of its attachment to the skin. If the tick does not spontaneously fall off within 20 minutes, it is carefully removed from the skin with tweezers and destroyed.

For comprehensive prevention of infections with fleas, ixodid ticks, round- and tapeworms, IN-UP complex is used after 6-7 weeks in the indicated doses.

To prevent dirofilariasis (infection with microfilariae), IN-UP complex is used throughout the entire spring-summer-autumn period: for the first time – once before the beginning of the mosquitoes and sand flies (carriers of dirofilariasis pathogen) summer, then every 6-7 weeks and for the last time during the season – in 1 month after the end of the summer of insects in the above specified doses.

When working with the antiparasitic agent, follow the general rules of personal hygiene and safety provided for when working with the medicinal products. Smoking, drinking, and eating are not allowed while applying the drug. After application, wash your hands thoroughly with warm water and soap.

Contact the manager of our company to fill out an application for the wholesale purchase trademark products of the IN-UP complex

There are contraindications. It is necessary to consult the specialist.
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